DeltaNotchCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 
00029 #ifndef DELTANOTCHCELLCYCLEMODEL_HPP_
00030 #define DELTANOTCHCELLCYCLEMODEL_HPP_
00031 
00032 #include "ChasteSerialization.hpp"
00033 #include <boost/serialization/base_object.hpp>
00034 
00035 #include "StochasticDurationGenerationBasedCellCycleModel.hpp"
00036 #include "DeltaNotchOdeSystem.hpp"
00037 #include "AbstractCellCycleModelOdeSolver.hpp"
00038 #include "CellCycleModelOdeHandler.hpp"
00039 
00048 class DeltaNotchCellCycleModel : public StochasticDurationGenerationBasedCellCycleModel, public CellCycleModelOdeHandler
00049 {
00050 private:
00051 
00053     friend class boost::serialization::access;
00060     template<class Archive>
00061     void serialize(Archive & archive, const unsigned int version)
00062     {
00063         archive & boost::serialization::base_object<StochasticDurationGenerationBasedCellCycleModel>(*this);
00064         archive & boost::serialization::base_object<CellCycleModelOdeHandler>(*this);
00065     }
00066 
00067 public:
00068 
00074     DeltaNotchCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>());
00075 
00082     AbstractCellCycleModel* CreateCellCycleModel();
00083 
00089     void Initialise();
00090 
00094     void UpdateCellCyclePhase();
00095 
00099     void UpdateDeltaNotch();
00100 
00104     double GetNotch();
00105 
00109     double GetDelta();
00110 
00114     double GetMeanNeighbouringDelta();
00115 
00121     virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
00122 };
00123 
00124 // Declare identifier for the serializer
00125 #include "SerializationExportWrapper.hpp"
00126 CHASTE_CLASS_EXPORT(DeltaNotchCellCycleModel)
00127 #include "CellCycleModelOdeSolverExportWrapper.hpp"
00128 EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(DeltaNotchCellCycleModel)
00129 
00130 #endif /*DELTANOTCHCELLCYCLEMODEL_HPP_*/
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