SimpleWntCellCycleModel.hpp

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*/
 
#ifndef SIMPLEWNTCELLCYCLEMODEL_HPP_
#define SIMPLEWNTCELLCYCLEMODEL_HPP_
 
#include "AbstractSimplePhaseBasedCellCycleModel.hpp"
#include "RandomNumberGenerator.hpp"
#include "WntConcentration.hpp"
 
class SimpleWntCellCycleModel : public AbstractSimplePhaseBasedCellCycleModel
{
private:
 
    friend class boost::serialization::access;
    template<class Archive>
    void serialize(Archive & archive, const unsigned int version)
    {
        archive & boost::serialization::base_object<AbstractSimplePhaseBasedCellCycleModel>(*this);
 
        RandomNumberGenerator* p_gen = RandomNumberGenerator::Instance();
        archive & *p_gen;
 
        archive & mUseCellProliferativeTypeDependentG1Duration;
        archive & mWntStemThreshold;
        archive & mWntTransitThreshold;
        archive & mWntLabelledThreshold;
    }
 
protected:
 
    bool mUseCellProliferativeTypeDependentG1Duration;
 
    double mWntStemThreshold;
 
    double mWntTransitThreshold;
 
    double mWntLabelledThreshold;
 
    double GetWntLevel() const;
 
    WntConcentrationType GetWntType();
 
    void SetG1Duration();
 
    SimpleWntCellCycleModel(const SimpleWntCellCycleModel& rModel);
 
public:
 
    SimpleWntCellCycleModel();
 
    virtual void UpdateCellCyclePhase();
 
    virtual void InitialiseDaughterCell();
 
    virtual AbstractCellCycleModel* CreateCellCycleModel();
 
    bool GetUseCellProliferativeTypeDependentG1Duration() const;
 
 
    void SetUseCellProliferativeTypeDependentG1Duration(bool useCellProliferativeTypeDependentG1Duration=true);
 
    virtual bool CanCellTerminallyDifferentiate();
 
    double GetWntStemThreshold() const;
 
    void SetWntStemThreshold(double wntStemThreshold);
 
    double GetWntTransitThreshold() const;
 
    void SetWntTransitThreshold(double wntTransitThreshold);
 
    double GetWntLabelledThreshold() const;
 
    void SetWntLabelledThreshold(double wntLabelledThreshold);
 
    virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
};
 
#include "SerializationExportWrapper.hpp"
// Declare identifier for the serializer
CHASTE_CLASS_EXPORT(SimpleWntCellCycleModel)
 
#endif /*SIMPLEWNTCELLCYCLEMODEL_HPP_*/