Chaste Commit::f2ff7ee04e70ac9d06c57344df8d017dbb12b97b
AbstractOdeSrnModel.cpp
1/*
2
3Copyright (c) 2005-2024, University of Oxford.
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10This file is part of Chaste.
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12Redistribution and use in source and binary forms, with or without
13modification, are permitted provided that the following conditions are met:
14 * Redistributions of source code must retain the above copyright notice,
15 this list of conditions and the following disclaimer.
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19 * Neither the name of the University of Oxford nor the names of its
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21 software without specific prior written permission.
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23THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
24AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
25IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
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32OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
33
34*/
35
36#include "AbstractOdeSrnModel.hpp"
37
38AbstractOdeSrnModel::AbstractOdeSrnModel(unsigned stateSize, boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver)
40 CellCycleModelOdeHandler(SimulationTime::Instance()->GetTime(), pOdeSolver),
41 mStateSize(stateSize)
42{
43}
44
46 : AbstractSrnModel(rModel),
48 mInitialConditions(rModel.mInitialConditions),
49 mStateSize(rModel.mStateSize)
50{
51 /*
52 * Set each member variable of the new SRN model that inherits
53 * its value from the parent.
54 *
55 * Note 1: some of the new SRN model's member variables
56 * will already have been correctly initialized in its constructor.
57 *
58 * Note 2: one or more of the new SRN model's member variables
59 * may be set/overwritten as soon as InitialiseDaughterCell() is called on
60 * the new SRN model.
61 *
62 * Note 3: Only set the variables defined in this class. Variables defined
63 * in parent classes will be defined there.
64 */
65}
66
70
72{
73 assert(mpOdeSystem != nullptr);
74 assert(SimulationTime::Instance()->IsStartTimeSetUp());
75
76 double current_time = SimulationTime::Instance()->GetTime();
77
78 // Run ODEs if needed
79 if (current_time > mLastTime)
80 {
81 if (!this->mFinishedRunningOdes)
82 {
83 // Update whether a stopping event has occurred
84 this->mFinishedRunningOdes = SolveOdeToTime(current_time);
85 }
86 else
87 {
88 // ODE model finished, just increasing time...
89 }
90 }
91
92 // Update the SimulatedToTime value
93 mLastTime = current_time;
94 SetSimulatedToTime(current_time);
95}
96
98{
99 assert(mpOdeSystem == nullptr);
100 assert(mpCell != nullptr);
101
102 mpOdeSystem = pOdeSystem;
103 if (mInitialConditions == std::vector<double>())
104 {
106 }
107 else
108 {
110 }
111
113}
114
121
122void AbstractOdeSrnModel::SetInitialConditions(std::vector<double> initialConditions)
123{
124 assert(initialConditions.size() == mStateSize);
125 mInitialConditions = initialConditions;
126}
127
129{
130 // No new parameters to output, so just call method on direct parent class
132}
133
135{
136 assert(mpOdeSystem != nullptr);
137 for (unsigned i=0; i<mpOdeSystem->GetNumberOfStateVariables(); ++i)
138 {
139 const double old_value = mpOdeSystem->GetStateVariable(i);
140 const double new_value = theta*old_value;
141 mpOdeSystem->SetStateVariable(i, new_value);
142 }
143}
144
145// Serialization for Boost >= 1.36
#define CHASTE_CLASS_EXPORT(T)
void SetInitialConditions(std::vector< double > initialConditions)
virtual void ScaleSrnVariables(const double theta)
std::vector< double > mInitialConditions
virtual void SimulateToCurrentTime()
virtual void Initialise()
virtual void OutputSrnModelParameters(out_stream &rParamsFile)
AbstractOdeSrnModel(const AbstractOdeSrnModel &rModel)
double GetStateVariable(unsigned index) const
void SetStateVariables(const VECTOR &rStateVariables)
void SetStateVariable(unsigned index, double newValue)
void SetSimulatedToTime(double simulatedToTime)
virtual void OutputSrnModelParameters(out_stream &rParamsFile)
virtual void ResetForDivision()
bool SolveOdeToTime(double currentTime)
double GetTime() const
static SimulationTime * Instance()