WntCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 
00029 #ifndef WNTCELLCYCLEMODEL_HPP_
00030 #define WNTCELLCYCLEMODEL_HPP_
00031 
00032 #include "ChasteSerialization.hpp"
00033 #include <boost/serialization/base_object.hpp>
00034 
00035 #include <cfloat>
00036 
00037 #include "AbstractWntOdeBasedCellCycleModel.hpp"
00038 #include "WntCellCycleOdeSystem.hpp"
00039 #include "AbstractCellMutationState.hpp"
00040 
00053 class WntCellCycleModel : public AbstractWntOdeBasedCellCycleModel
00054 {
00055 private:
00057     friend class boost::serialization::access;
00064     template<class Archive>
00065     void serialize(Archive & archive, const unsigned int version)
00066     {
00067         archive & boost::serialization::base_object<AbstractWntOdeBasedCellCycleModel>(*this);
00068     }
00069 
00078     void ChangeCellProliferativeTypeDueToCurrentBetaCateninLevel();
00079 
00085     void AdjustOdeParameters(double currentTime);
00086 
00087 public:
00088 
00094     WntCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>());
00095 
00100     AbstractCellCycleModel* CreateCellCycleModel();
00101 
00109     void Initialise();
00110 
00116     virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
00117 };
00118 
00119 // Declare identifier for the serializer
00120 #include "SerializationExportWrapper.hpp"
00121 CHASTE_CLASS_EXPORT(WntCellCycleModel)
00122 #include "CellCycleModelOdeSolverExportWrapper.hpp"
00123 EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(WntCellCycleModel)
00124 
00125 #endif /*WNTCELLCYCLEMODEL_HPP_*/
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