Chaste  Release::2018.1
SimpleWntCellCycleModel.hpp
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34 */
35 
36 #ifndef SIMPLEWNTCELLCYCLEMODEL_HPP_
37 #define SIMPLEWNTCELLCYCLEMODEL_HPP_
38 
39 #include "AbstractSimplePhaseBasedCellCycleModel.hpp"
40 #include "RandomNumberGenerator.hpp"
41 #include "WntConcentration.hpp"
42 
47 {
48 private:
49 
58  template<class Archive>
59  void serialize(Archive & archive, const unsigned int version)
60  {
61  archive & boost::serialization::base_object<AbstractSimplePhaseBasedCellCycleModel>(*this);
62 
64  archive & *p_gen;
65 
67  archive & mWntStemThreshold;
68  archive & mWntTransitThreshold;
69  archive & mWntLabelledThreshold;
70  }
71 
72 protected:
73 
79 
84 
89 
94 
98  double GetWntLevel() const;
99 
104  WntConcentrationType GetWntType();
105 
115  void SetG1Duration();
116 
131 
132 public:
133 
139 
143  virtual void UpdateCellCyclePhase();
144 
148  virtual void InitialiseDaughterCell();
149 
157 
162 
163 
168  void SetUseCellProliferativeTypeDependentG1Duration(bool useCellProliferativeTypeDependentG1Duration=true);
169 
174  virtual bool CanCellTerminallyDifferentiate();
175 
179  double GetWntStemThreshold() const;
180 
186  void SetWntStemThreshold(double wntStemThreshold);
187 
191  double GetWntTransitThreshold() const;
192 
198  void SetWntTransitThreshold(double wntTransitThreshold);
199 
203  double GetWntLabelledThreshold() const;
204 
210  void SetWntLabelledThreshold(double wntLabelledThreshold);
211 
217  virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
218 };
219 
221 // Declare identifier for the serializer
223 
224 #endif /*SIMPLEWNTCELLCYCLEMODEL_HPP_*/
friend class boost::serialization::access
virtual void OutputCellCycleModelParameters(out_stream &rParamsFile)
WntConcentrationType GetWntType()
virtual AbstractCellCycleModel * CreateCellCycleModel()
void serialize(Archive &archive, const unsigned int version)
bool GetUseCellProliferativeTypeDependentG1Duration() const
void SetUseCellProliferativeTypeDependentG1Duration(bool useCellProliferativeTypeDependentG1Duration=true)
void SetWntTransitThreshold(double wntTransitThreshold)
static RandomNumberGenerator * Instance()
void SetWntLabelledThreshold(double wntLabelledThreshold)
#define CHASTE_CLASS_EXPORT(T)
void SetWntStemThreshold(double wntStemThreshold)
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