Chaste Release::3.1
SloughingCellKiller.cpp
00001 /*
00002 
00003 Copyright (c) 2005-2012, University of Oxford.
00004 All rights reserved.
00005 
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00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
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00015    this list of conditions and the following disclaimer.
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00034 */
00035 #include "SloughingCellKiller.hpp"
00036 #include "AbstractCentreBasedCellPopulation.hpp"
00037 #include "Exception.hpp"
00038 
00039 template<unsigned DIM>
00040 SloughingCellKiller<DIM>::SloughingCellKiller(AbstractCellPopulation<DIM>* pCrypt, double sloughHeight, bool sloughSides, double sloughWidth)
00041     : AbstractCellKiller<DIM>(pCrypt),
00042       mSloughSides(sloughSides)
00043 {
00044     assert(sloughHeight > 0.0);
00045     mSloughHeight = sloughHeight;
00046 
00047     assert(sloughWidth > 0.0);
00048     mSloughWidth = sloughWidth;
00049 }
00050 
00051 template<unsigned DIM>
00052 bool SloughingCellKiller<DIM>::GetSloughSides() const
00053 {
00054     return mSloughSides;
00055 }
00056 
00057 template<unsigned DIM>
00058 double SloughingCellKiller<DIM>::GetSloughHeight() const
00059 {
00060     return mSloughHeight;
00061 }
00062 
00063 template<unsigned DIM>
00064 double SloughingCellKiller<DIM>::GetSloughWidth() const
00065 {
00066     return mSloughWidth;
00067 }
00068 
00069 template<unsigned DIM>
00070 void SloughingCellKiller<DIM>::CheckAndLabelCellsForApoptosisOrDeath()
00071 {
00072     switch (DIM)
00073     {
00074         case 1:
00075         {
00076             for (typename AbstractCellPopulation<DIM>::Iterator cell_iter = this->mpCellPopulation->Begin();
00077                  cell_iter != this->mpCellPopulation->End();
00078                  ++cell_iter)
00079             {
00080                 double x = this->mpCellPopulation->GetLocationOfCellCentre(*cell_iter)[0];
00081 
00082                 if (x > mSloughHeight)
00083                 {
00084                     cell_iter->Kill();
00085                 }
00086             }
00087             break;
00088         }
00089         case 2:
00090         {
00091             for (typename AbstractCellPopulation<DIM>::Iterator cell_iter = this->mpCellPopulation->Begin();
00092                  cell_iter != this->mpCellPopulation->End();
00093                  ++cell_iter)
00094             {
00095                 c_vector<double, 2> location = this->mpCellPopulation->GetLocationOfCellCentre(*cell_iter);
00096                 double x = location[0];
00097                 double y = location[1];
00098 
00099                 if ((y>mSloughHeight) || (mSloughSides && ((x<0.0) || (x>mSloughWidth))))
00100                 {
00101                     cell_iter->Kill();
00102                 }
00103             }
00104             break;
00105         }
00106         case 3:
00107         {
00108             EXCEPTION("SloughingCellKiller is not yet implemented in 3D");
00109             break;
00110         }
00111         default:
00112             // This can't happen
00113             NEVER_REACHED;
00114     }
00115 }
00116 
00117 template<unsigned DIM>
00118 void SloughingCellKiller<DIM>::OutputCellKillerParameters(out_stream& rParamsFile)
00119 {
00120     *rParamsFile << "\t\t\t<SloughLength>" << mSloughHeight << "</SloughLength>\n";
00121     *rParamsFile << "\t\t\t<SloughSides>" << mSloughSides << "</SloughSides>\n";
00122     *rParamsFile << "\t\t\t<SloughWidth>" << mSloughWidth << "</SloughWidth>\n";
00123 
00124     // Call method on direct parent class
00125     AbstractCellKiller<DIM>::OutputCellKillerParameters(rParamsFile);
00126 }
00127 
00129 // Explicit instantiation
00131 
00132 template class SloughingCellKiller<1>;
00133 template class SloughingCellKiller<2>;
00134 template class SloughingCellKiller<3>;
00135 
00136 // Serialization for Boost >= 1.36
00137 #include "SerializationExportWrapperForCpp.hpp"
00138 EXPORT_TEMPLATE_CLASS_SAME_DIMS(SloughingCellKiller)