Chaste Release::3.1
RandomCellKiller.hpp
00001 /*
00002 
00003 Copyright (c) 2005-2012, University of Oxford.
00004 All rights reserved.
00005 
00006 University of Oxford means the Chancellor, Masters and Scholars of the
00007 University of Oxford, having an administrative office at Wellington
00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
00011 
00012 Redistribution and use in source and binary forms, with or without
00013 modification, are permitted provided that the following conditions are met:
00014  * Redistributions of source code must retain the above copyright notice,
00015    this list of conditions and the following disclaimer.
00016  * Redistributions in binary form must reproduce the above copyright notice,
00017    this list of conditions and the following disclaimer in the documentation
00018    and/or other materials provided with the distribution.
00019  * Neither the name of the University of Oxford nor the names of its
00020    contributors may be used to endorse or promote products derived from this
00021    software without specific prior written permission.
00022 
00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
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00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT
00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
00033 
00034 */
00035 
00036 #ifndef RANDOMCELLKILLER_HPP_
00037 #define RANDOMCELLKILLER_HPP_
00038 
00039 #include "AbstractCellKiller.hpp"
00040 #include "RandomNumberGenerator.hpp"
00041 
00042 #include "ChasteSerialization.hpp"
00043 #include <boost/serialization/base_object.hpp>
00044 
00045 
00062 template<unsigned DIM>
00063 class RandomCellKiller : public AbstractCellKiller<DIM>
00064 {
00065 private:
00066 
00071      double mProbabilityOfDeathInAnHour;
00072 
00074     friend class boost::serialization::access;
00081     template<class Archive>
00082     void serialize(Archive & archive, const unsigned int version)
00083     {
00084         archive & boost::serialization::base_object<AbstractCellKiller<DIM> >(*this);
00085 
00086         // Make sure the random number generator is also archived
00087         SerializableSingleton<RandomNumberGenerator>* p_rng_wrapper = RandomNumberGenerator::Instance()->GetSerializationWrapper();
00088         archive & p_rng_wrapper;
00089     }
00090 
00091 public:
00092 
00099     RandomCellKiller(AbstractCellPopulation<DIM>* pCellPopulation, double probabilityOfDeathInAnHour);
00100 
00104     double GetDeathProbabilityInAnHour() const;
00105 
00111     void CheckAndLabelSingleCellForApoptosis(CellPtr pCell);
00112 
00117     void CheckAndLabelCellsForApoptosisOrDeath();
00118 
00124     void OutputCellKillerParameters(out_stream& rParamsFile);
00125 };
00126 
00127 #include "SerializationExportWrapper.hpp"
00128 EXPORT_TEMPLATE_CLASS_SAME_DIMS(RandomCellKiller)
00129 
00130 namespace boost
00131 {
00132 namespace serialization
00133 {
00137 template<class Archive, unsigned DIM>
00138 inline void save_construct_data(
00139     Archive & ar, const RandomCellKiller<DIM> * t, const BOOST_PFTO unsigned int file_version)
00140 {
00141     // Save data required to construct instance
00142     const AbstractCellPopulation<DIM>* const p_cell_population = t->GetCellPopulation();
00143     ar << p_cell_population;
00144     double prob = t->GetDeathProbabilityInAnHour();
00145     ar << prob;
00146 }
00147 
00151 template<class Archive, unsigned DIM>
00152 inline void load_construct_data(
00153     Archive & ar, RandomCellKiller<DIM> * t, const unsigned int file_version)
00154 {
00155     // Retrieve data from archive required to construct new instance
00156     AbstractCellPopulation<DIM>* p_cell_population;
00157     ar >> p_cell_population;
00158     double prob;
00159     ar >> prob;
00160 
00161     // Invoke inplace constructor to initialise instance
00162     ::new(t)RandomCellKiller<DIM>(p_cell_population, prob);
00163 }
00164 }
00165 } // namespace ...
00166 
00167 #endif /*RANDOMCELLKILLER_HPP_*/