WntCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef WNTCELLCYCLEMODEL_HPP_
00029 #define WNTCELLCYCLEMODEL_HPP_
00030 
00031 #include "ChasteSerialization.hpp"
00032 #include <boost/serialization/base_object.hpp>
00033 
00034 #include <cfloat>
00035 
00036 #include "AbstractWntOdeBasedCellCycleModel.hpp"
00037 #include "WntCellCycleOdeSystem.hpp"
00038 #include "AbstractCellMutationState.hpp"
00039 
00052 class WntCellCycleModel : public AbstractWntOdeBasedCellCycleModel
00053 {
00054 private:
00056     friend class boost::serialization::access;
00063     template<class Archive>
00064     void serialize(Archive & archive, const unsigned int version)
00065     {
00066         archive & boost::serialization::base_object<AbstractWntOdeBasedCellCycleModel>(*this);
00067     }
00068 
00077     void ChangeCellProliferativeTypeDueToCurrentBetaCateninLevel();
00078 
00084     void AdjustOdeParameters(double currentTime);
00085 
00086 public:
00087 
00093     WntCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>());
00094 
00099     AbstractCellCycleModel* CreateCellCycleModel();
00100 
00108     void Initialise();
00109 
00115     virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
00116 };
00117 
00118 // Declare identifier for the serializer
00119 #include "SerializationExportWrapper.hpp"
00120 CHASTE_CLASS_EXPORT(WntCellCycleModel)
00121 #include "CellCycleModelOdeSolverExportWrapper.hpp"
00122 EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(WntCellCycleModel)
00123 
00124 #endif /*WNTCELLCYCLEMODEL_HPP_*/

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