TysonNovakCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef TYSONNOVAKCELLCYCLEMODEL_HPP_
00029 #define TYSONNOVAKCELLCYCLEMODEL_HPP_
00030 
00031 #include "ChasteSerialization.hpp"
00032 #include <boost/serialization/base_object.hpp>
00033 
00034 #include "AbstractOdeBasedCellCycleModel.hpp"
00035 #include "TysonNovak2001OdeSystem.hpp"
00036 
00037 
00047 class TysonNovakCellCycleModel : public AbstractOdeBasedCellCycleModel
00048 {
00049 private:
00050 
00051     friend class TestOdeBasedCellCycleModels;
00052 
00054     friend class boost::serialization::access;
00061     template<class Archive>
00062     void serialize(Archive & archive, const unsigned int version)
00063     {
00064         archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this);
00065     }
00066 
00067 public:
00068 
00074     TysonNovakCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>());
00075 
00087     void Initialise();
00088 
00093     void ResetForDivision();
00094 
00099     AbstractCellCycleModel* CreateCellCycleModel();
00100 
00104     double GetSDuration();
00105 
00109     double GetG2Duration();
00110 
00114     double GetMDuration();
00115 
00119     void InitialiseDaughterCell();
00120 
00124     double GetAverageTransitCellCycleTime();
00125 
00129     double GetAverageStemCellCycleTime();
00130 
00134     bool CanCellTerminallyDifferentiate();
00135 
00141     virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
00142 };
00143 
00144 // Declare identifier for the serializer
00145 #include "SerializationExportWrapper.hpp"
00146 CHASTE_CLASS_EXPORT(TysonNovakCellCycleModel)
00147 #include "CellCycleModelOdeSolverExportWrapper.hpp"
00148 EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(TysonNovakCellCycleModel)
00149 
00150 #endif /*TYSONNOVAKCELLCYCLEMODEL_HPP_*/

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