AbstractCardiacCellInterface.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 
00029 #ifndef ABSTRACTCARDIACCELLINTERFACE_HPP_
00030 #define ABSTRACTCARDIACCELLINTERFACE_HPP_
00031 
00032 #include <boost/shared_ptr.hpp>
00033 
00034 #include "ChasteSerialization.hpp"
00035 #include "ClassIsAbstract.hpp"
00036 
00037 #include "AbstractIvpOdeSolver.hpp"
00038 #include "AbstractStimulusFunction.hpp"
00039 #include "OdeSolution.hpp"
00040 #include "AbstractLookupTableCollection.hpp"
00041 
00054 class AbstractCardiacCellInterface
00055 {
00056 public:
00069     AbstractCardiacCellInterface(boost::shared_ptr<AbstractIvpOdeSolver> pOdeSolver,
00070                                  unsigned voltageIndex,
00071                                  boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus);
00072 
00074     virtual ~AbstractCardiacCellInterface();
00075 
00079     virtual void ResetToInitialConditions()=0;
00080 
00086     virtual void SetTimestep(double dt)=0;
00087 
00096     virtual void SolveAndUpdateState(double tStart, double tEnd)=0;
00097 
00107     virtual OdeSolution Compute(double tStart, double tEnd, double tSamp=0.0)=0;
00108 
00117     virtual void ComputeExceptVoltage(double tStart, double tEnd)=0;
00118 
00144     virtual double GetIIonic(const std::vector<double>* pStateVariables=NULL)=0;
00145 
00149     virtual void SetVoltage(double voltage)=0;
00150 
00155     virtual double GetVoltage()=0;
00156 
00163     unsigned GetVoltageIndex();
00164 
00170     void SetStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus);
00171 
00177     double GetStimulus(double time);
00178 
00185     void SetIntracellularStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus);
00186 
00194     double GetIntracellularStimulus(double time);
00195 
00202     double GetIntracellularAreaStimulus(double time);
00203 
00212     void SetUsedInTissueSimulation(bool tissue=true);
00213 
00220     virtual void UseCellMLDefaultStimulus();
00221 
00225     bool HasCellMLDefaultStimulus();
00226 
00234     virtual void VerifyStateVariables()
00235     {
00236         // See also #794.
00237     }
00238 
00245     virtual AbstractLookupTableCollection* GetLookupTableCollection()
00246     {
00247         return NULL;
00248     }
00249 
00253     boost::shared_ptr<AbstractStimulusFunction> GetStimulusFunction();
00254 
00261     const boost::shared_ptr<AbstractStimulusFunction> GetStimulusFunction() const;
00262 
00269     const boost::shared_ptr<AbstractIvpOdeSolver> GetSolver() const;
00270 
00271 protected:
00278     unsigned mVoltageIndex;
00279 
00281     boost::shared_ptr<AbstractIvpOdeSolver> mpOdeSolver;
00282 
00284     boost::shared_ptr<AbstractStimulusFunction> mpIntracellularStimulus;
00285 
00291     bool mSetVoltageDerivativeToZero;
00292 
00294     bool mIsUsedInTissue;
00295 
00297     bool mHasDefaultStimulusFromCellML;
00298 
00299 private:
00301     friend class boost::serialization::access;
00311     template<class Archive>
00312     void serialize(Archive & archive, const unsigned int version)
00313     {
00314     }
00315 };
00316 
00317 CLASS_IS_ABSTRACT(AbstractCardiacCellInterface)
00318 
00319 
00320 #endif /*ABSTRACTCARDIACCELLINTERFACE_HPP_*/

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