00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2010 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #include "StochasticWntCellCycleModel.hpp" 00029 00030 00031 StochasticWntCellCycleModel::StochasticWntCellCycleModel() 00032 { 00033 } 00034 00035 00036 StochasticWntCellCycleModel::StochasticWntCellCycleModel(const std::vector<double>& rParentProteinConcentrations, 00037 boost::shared_ptr<AbstractCellMutationState> pMutationState, 00038 const unsigned& rDimension) 00039 : WntCellCycleModel(rParentProteinConcentrations, pMutationState, rDimension) 00040 { 00041 } 00042 00043 00044 void StochasticWntCellCycleModel::SetG2Duration() 00045 { 00046 TissueConfig* p_config = TissueConfig::Instance(); 00047 RandomNumberGenerator* p_gen = RandomNumberGenerator::Instance(); 00048 00049 double mean = p_config->GetG2Duration(); 00050 double standard_deviation = 0.9; 00051 00052 mG2Duration = p_gen->NormalRandomDeviate(mean, standard_deviation); 00053 00054 // Check that the normal random deviate has not returned a small or negative G2 duration 00055 if (mG2Duration < p_config->GetMinimumGapDuration()) 00056 { 00057 #define COVERAGE_IGNORE 00058 mG2Duration = p_config->GetMinimumGapDuration(); 00059 #undef COVERAGE_IGNORE 00060 } 00061 } 00062 00063 00064 void StochasticWntCellCycleModel::InitialiseDaughterCell() 00065 { 00066 SetG2Duration(); 00067 } 00068 00069 00070 void StochasticWntCellCycleModel::Initialise() 00071 { 00072 WntCellCycleModel::Initialise(); 00073 SetG2Duration(); 00074 } 00075 00076 00077 void StochasticWntCellCycleModel::ResetForDivision() 00078 { 00079 AbstractWntOdeBasedCellCycleModel::ResetForDivision(); 00080 SetG2Duration(); 00081 } 00082 00083 00084 double StochasticWntCellCycleModel::GetG2Duration() 00085 { 00086 return mG2Duration; 00087 } 00088 00089 00090 AbstractCellCycleModel* StochasticWntCellCycleModel::CreateCellCycleModel() 00091 { 00092 return new StochasticWntCellCycleModel(*this); 00093 } 00094 00095 00096 // Serialization for Boost >= 1.36 00097 #include "SerializationExportWrapperForCpp.hpp" 00098 CHASTE_CLASS_EXPORT(StochasticWntCellCycleModel)