WntConcentration.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2009
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef WNTCONCENTRATION_HPP_
00029 #define WNTCONCENTRATION_HPP_
00030 
00031 #include <boost/serialization/access.hpp>
00032 #include <boost/serialization/base_object.hpp>
00033 
00034 #include <iostream>
00035 
00036 #include "MeshBasedTissue.hpp"
00037 
00038 // Needs to be included last
00039 #include <boost/serialization/export.hpp>
00040 
00047 typedef enum WntConcentrationType_
00048 {
00049     NONE,
00050     LINEAR,
00051     RADIAL
00052 } WntConcentrationType;
00053 
00054 
00058 class WntConcentration
00059 {
00060 private:
00061 
00063     static WntConcentration* mpInstance;
00064 
00066     CancerParameters* mpCancerParams;
00067 
00074     WntConcentrationType mWntType;
00075 
00079     AbstractTissue<2>* mpTissue;
00080 
00084     bool mTypeSet;
00085 
00089     double mConstantWntValueForTesting;
00090 
00095     bool mUseConstantWntValueForTesting;
00096 
00098     friend class boost::serialization::access;
00105     template<class Archive>
00106     void serialize(Archive & archive, const unsigned int version)
00107     {
00108         mpCancerParams = CancerParameters::Instance();
00109         archive & *mpCancerParams;
00110         archive & mpCancerParams;
00111         archive & mWntType;
00112         archive & mpTissue;
00113         archive & mTypeSet;
00114         archive & mConstantWntValueForTesting;
00115         archive & mUseConstantWntValueForTesting;
00116     }
00117 
00118 protected:
00119 
00123     WntConcentration();
00124 
00125 public:
00126 
00133     static WntConcentration* Instance();
00134 
00138     virtual ~WntConcentration();
00139 
00144     static void Destroy();
00145 
00153     double GetWntLevel(double height);
00154 
00163     double GetWntLevel(TissueCell* pCell);
00164 
00171     c_vector<double,2> GetWntGradient(c_vector<double,2> location);
00172 
00180     c_vector<double,2> GetWntGradient(TissueCell* pCell);
00181 
00187     void SetTissue(AbstractTissue<2>& rTissue);
00188 
00192     WntConcentrationType GetType();
00193 
00199     void SetType(WntConcentrationType type);
00200 
00207     void SetConstantWntValueForTesting(double value);
00208 
00219     bool IsWntSetUp();
00220 
00221 };
00222 
00223 BOOST_CLASS_EXPORT(WntConcentration);
00224 
00225 #endif /*WNTCONCENTRATION_HPP_*/

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