RandomCellKiller.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2009
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef RANDOMCELLKILLER_HPP_
00029 #define RANDOMCELLKILLER_HPP_
00030 
00031 #include "AbstractCellKiller.hpp"
00032 #include "RandomNumberGenerator.hpp"
00033 
00034 #include <boost/serialization/access.hpp>
00035 #include <boost/serialization/base_object.hpp>
00036 
00037 
00048 template <unsigned SPACE_DIM>
00049 class RandomCellKiller : public AbstractCellKiller<SPACE_DIM>
00050 {
00051 private:
00052 
00054     double mProbabilityOfDeath;
00055 
00057     friend class boost::serialization::access;
00068     template<class Archive>
00069     void serialize(Archive & archive, const unsigned int version)
00070     {
00071         archive & boost::serialization::base_object<AbstractCellKiller<SPACE_DIM> >(*this);
00072    
00073         // Make sure the random number generator is archived
00074         RandomNumberGenerator* p_random_generator = RandomNumberGenerator::Instance();
00075         archive & *p_random_generator;
00076         archive & p_random_generator;
00077     }
00078 
00079 public:
00080 
00087     RandomCellKiller(AbstractTissue<SPACE_DIM>* pTissue, double probabilityOfDeath);
00088 
00092     double GetDeathProbability() const;
00093 
00099     void TestAndLabelSingleCellForApoptosis(TissueCell& rCell);
00100 
00105     void TestAndLabelCellsForApoptosisOrDeath();
00106 
00107 };
00108 
00109 #include "TemplatedExport.hpp"
00110 
00111 EXPORT_TEMPLATE_CLASS_SAME_DIMS(RandomCellKiller)
00112 
00113 namespace boost
00114 {
00115 namespace serialization
00116 {
00120 template<class Archive, unsigned DIM>
00121 inline void save_construct_data(
00122     Archive & ar, const RandomCellKiller<DIM> * t, const BOOST_PFTO unsigned int file_version)
00123 {
00124     // Save data required to construct instance
00125     const AbstractTissue<DIM>* const p_tissue = t->GetTissue();
00126     ar << p_tissue;
00127     double prob = t->GetDeathProbability();
00128     ar << prob;
00129 }
00130 
00134 template<class Archive, unsigned DIM>
00135 inline void load_construct_data(
00136     Archive & ar, RandomCellKiller<DIM> * t, const unsigned int file_version)
00137 {
00138     // Retrieve data from archive required to construct new instance
00139     AbstractTissue<DIM>* p_tissue;
00140     ar >> p_tissue;
00141     double prob;
00142     ar >> prob;
00143 
00144     // Invoke inplace constructor to initialise instance
00145     ::new(t)RandomCellKiller<DIM>(p_tissue, prob);
00146 }
00147 }
00148 } // namespace ...
00149 
00150 #endif /*RANDOMCELLKILLER_HPP_*/

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